Antioxidant and anticolinesterasic effects of Hippeastrum species (Amaryllidaceae)

Química Nova

Pagliosa, Letícia Balvedi¹  Henriques, Amélia T.¹  Giordani, Raquel Brandt¹  Dutilh, Julie H. A.¹  Universidade Estadual de Campinas, Campinas, Brasil¹  Universidade Federal do Rio Grande do Sul, Porto Alegre, Brasil¹  Zuanazzi, José Angelo S.¹ 

关键词: Amaryllidaceae;    antioxidant;    anticholinesterasic.;   

DOI  :  10.1590/S0100-40422008000800024

学科分类：化学（综合）

来源: Sociedade Brasileira de Quimica

【 摘 要 】

Amaryllidaceae family is an important source of bioactive molecules and considering the taxonomic relationships, it is relevant to investigate the genus Hippeastrum. Thus, the aim of this work was to determine antioxidant and anticholinesterasic activities of Hippeastrum morelianum, Hippeastrum psittacinum and Hippeastrum santacatarina. Both antioxidant and acetylcholinesterasic activities of extracts were determinated by bioautography as 10 mg/mL and 0.1 mg/mL, respectively. The antioxidant activity of alkaloid lycorine, determinated spectrophotometrically with DPPH, indicated an IC50 value of 0.326 mM.

【 授权许可】

Unknown