Optimization of the extraction and isolation of the antimalarial drug artemisinin from Artemisia annua L.

Química Nova

Foglio, Mary Ann¹  Rehder, Vera Lúcia Garcia¹  Boaventura Júnior, Sinésio¹  Santos, Adriana da Silva¹  Rodrigues, Rodney Alexandre Ferreira¹  Universidade Estadual de Campinas¹ 

关键词: malaria;    artemisinin production;    Artemisia annua L.;   

DOI  :  10.1590/S0100-40422006000200030

学科分类：化学（综合）

来源: Sociedade Brasileira de Quimica

【 摘 要 】

Malaria is still one of the major diseases in the world, causing physical and economic problems in tropical regions. Artemisinin (Qinghaosu), a natural compound identified in Artemisia annua L. , is an effective drug mainly against cerebral malaria. The action of this drug is immediate and parasitaemia in the treatment of drug-resistant malaria is rapidily reduced, justifying the industrial production of artemisinin. This article focuses on the industrial production of this potent antimalarial drug, including strategies for enhancing yield using inexpensive and easy steps.

【 授权许可】

Unknown