Optimization of the extraction and isolation of the antimalarial drug artemisinin from Artemisia annua L.

Quimica nova

Foglio, Mary Ann¹  Rehder, Vera Lúcia Garcia¹  Boaventura Júnior, Sinésio¹  Santos, Adriana da Silva¹  Rodrigues, Rodney Alexandre Ferreira¹ 

[1] Universidade Estadual de Campinas

关键词: malaria;    artemisinin production;    Artemisia annua L.;   

DOI  :  10.1590/S0100-40422006000200030

学科分类：化学（综合）

来源: Sociedade Brasileira de Quimica

【 摘 要 】

Malaria is stillone of the major diseases in the world, causing physical and economic problemsin tropical regions. Artemisinin (Qinghaosu), a natural compound identifiedin Artemisia annua L. , is an effective drug mainly against cerebralmalaria. The action of this drug is immediate and parasitaemia in the treatmentof drug-resistant malaria is rapidily reduced, justifying the industrial productionof artemisinin. This article focuses on the industrial production of this potentantimalarial drug, including strategies for enhancing yield using inexpensiveand easy steps.

【 授权许可】

CC BY