Phytochemical study and evaluation of the molluscicidal activity of Calophyllum brasiliense Camb (Clusiaceae)

Química Nova

Brenzan, Mislaine Adriana¹  Ferreira, Antonio Gilberto¹  Nakamura, Celso Vataru¹  Piloto, Izabel Cristina¹  Cortez, Diógenes Aparício Garcia¹  Universidade Federal de São Carlos, São Carlos¹  Rodrigues Filho, Edson¹  Dias Filho, Benedito Prado¹  Gasparotto Jr., Arquimedes¹  Universidade Estadual de Maringá, Maringá¹ 

关键词: Calophyllum brasiliense;    molluscicidal activity;    coumarin.;   

DOI  :  10.1590/S0100-40422005000400003

学科分类：化学（综合）

来源: Sociedade Brasileira de Quimica

【 摘 要 】

The bioassay-guided fractionation against Biomphalaria glabrata of hydroalcoholic extracts of Calophyllum brasiliense aerial parts led to the isolation of the coumarin, named (-) mammea A/BB. The compound had its structure determined by both spectroscopic techniques (NMR 1H, NMR 13C, gHSQC, gHMBC and MS) and some literature comparison data. The probit analysis of (-) mammea A/BB showed LD50 = 0.67 ppm and LD90 = 1.47 ppm. In addition, the dichloromethane extract obtained from C. brasiliense leaves with significant molluscicidal activity against Biomphalaria glabrata was analyzed by HPLC-UV.

【 授权许可】

Unknown