Intramolecular reactions as non mimetic models of enzyme catalysis

Química Nova

Yunes, Santiago¹  Clementin, Rosilene M.¹  Nome, Faruk¹  Universidade Federal de Santa Catarina, Florianópolis¹  Gesser, José Carlos¹ 

关键词: enzymatic catalysis;    intramolecular reactions;    nonmimetic enzyme models.;   

DOI  :  10.1590/S0100-40421997000600011

学科分类：化学（综合）

来源: Sociedade Brasileira de Quimica

【 摘 要 】

This review gives a critical idea on the importance of intramolecular reactions as models for enzymatic catalysis. Intramolecular lactonizations, ester and amide hydrolysis studies result in theories which try to explain the difference between intermolecular, intramolecular and enzyme reactions and rationalize the enhancement promoted by these biological catalyst.

【 授权许可】

Unknown