Reações intramoleculares como modelos não miméticos de catálise enzimática

Química Nova

José Carlos Gesser¹  Santiago Yunes¹  Rosilene M. Clementin¹  Faruk Nome¹ 

[1] ,Universidade Federal de Santa Catarina Departamento de Química Florianópolis SC

关键词: enzymatic catalysis;    intramolecular reactions;    nonmimetic enzyme models;   

DOI  :  10.1590/S0100-40421997000600011

来源: SciELO

【 摘 要 】

This review gives a critical idea on the importance of intramolecular reactions as models for enzymatic catalysis. Intramolecular lactonizations, ester and amide hydrolysis studies result in theories which try to explain the difference between intermolecular, intramolecular and enzyme reactions and rationalize the enhancement promoted by these biological catalyst.

【 授权许可】

CC BY-NC   
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