期刊论文详细信息
Journal of the Brazilian Chemical Society | |
Plastic membrane, carbon paste and multiwalled carbon nanotube composite coated copper wire sensors for determination of oxeladin citrate using batch and flow injection techniques | |
Zayed, Sayed I. M.1  Issa, Yousry M.1  Taif University, Taif, Kingdom of Saudi Arabia1  Cairo University, Giza, Egypt1  Beni Suef University, Beni Suef, Egypt1  | |
关键词: oxeladin citrate; potentiometry; flow injection; pharmaceutical formulation; human urine; | |
DOI : 10.5935/0103-5053.20130069 | |
学科分类:化学(综合) | |
来源: SciELO | |
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【 摘 要 】
The fabrication and performance characteristics of three novel potentiometric sensors for the determination of oxeladin citrate are described. The proposed sensors include a PVC plastic membrane sensor, a carbon paste sensor and a multiwalled carbon nanotube (MWCNT) composite coated copper wire sensor. The sensors are based on the oxeladin-phosphotungstate ion associate as electroactive material and dibutyl phthalate as solvent mediator. The developed sensors exhibited near nernstian slopes of 58.00 ± 0.22, 55.00 ± 0.69 and 57.8 ± 0.13 mV concentration decade-1 at 25 ºC, in the concentration ranges 5.96 × 10-6 - 1.00 × 10-2, 1.96 × 10-5 - 1.00 × 10-2 and 3.98 × 10-6 - 1.00 × 10-2 mol L-1 oxeladin citrate with limits of detection of 4.14 × 10-6, 8.58 × 10-6 and 2.51 × 10-6 mol L-1 oxeladin citrate for plastic membrane, carbon paste and MWCNT composite coated copper wire sensors, respectively. The proposed sensors exhibit good selectivity for oxeladin with respect to a large number of inorganic cations, sugars, amino acids and vitamins. The developed sensors were successfully applied for the potentiometric determination of oxeladin citrate in the pharmaceutical preparation (Paxeladine® capsules) in batch and flow injection conditions. The sensors were also applied for the determination of oxeladin citrate in human urine samples by using the standard addition method.【 授权许可】
Unknown
【 预 览 】
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RO201912050581878ZK.pdf | 634KB | ![]() |