期刊论文详细信息
| Journal of the Brazilian Chemical Society | |
| Synthesis and antiacetylcholinesterase activity of new D-glyceraldehyde heterocyclic derivatives | |
| D'Accorso, Norma B.1 Fascio, Mirta L.1 Universidad de Buenos Aires, Buenos Aires, Argentina1 Saavedra, Luís Astudillo1 Universidad de Talca, Talca, Chile1 Cabrera, Margarita Gutiérrez1 Scorzo, Cecilia M.1 | |
| 关键词: D-glyceraldehyde; heterocyclic compounds; cycloaddition; acetylcholinesterase; Alzheimer´s disease; | |
| DOI : 10.1590/S0103-50532010000100008 | |
| 学科分类：化学（综合） | |
| 来源: SciELO | |
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【 摘 要 】
We report herein the convenient procedures for the syntheses of different heterocyclic compounds from 2,3-O-isopropylidene-D-glyceraldehyde using intramolecular cyclization, 1,3-dipolar cycloaddition or bimolecular coupling reactions. The products were characterized by 1H and 13C NMR spectroscopy and elemental analysis. The new heterocycles and their derivatives were evaluated as inhibitors of acetylcholinesterase enzyme.
【 授权许可】
Unknown
【 预 览 】
| Files | Size | Format | View |
|---|---|---|---|
| RO201912050580817ZK.pdf | 171KB |  download |
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