Chemoselective synthesis of novel thiatriazolophanes

Journal of the Brazilian Chemical Society

Puthamane, Kiran A.¹  Chande, Madhukar S.¹  The Institute of Science, Mumbai, India¹  Venkataraman, Deepak S.¹  Khanwelkar, Rahul R.¹  Barve, Pravin A.¹ 

关键词: 4-alkyl/aryl-5-thia-1;    2;    4-triazoles;    1;    w-dihaloalkanes;    N-alkyl/aryl thiatriazolophanes;    chemoselectivity;   

DOI  :  10.1590/S0103-50532008000100008

学科分类：化学（综合）

来源: SciELO

【 摘 要 】

Bis-[4-alkyl/aryl-5-thia-1,2,4-triazoles] were prepared by fusion of diacids and thiosemicarbazides by condensation of aromatic acid hydrazides with isothiocyanate. Chemoselective alkylation of these bis-[4-alkyl/aryl-5-thia-1,2,4-triazoles] with 1,w-dihaloalkanes in presence of potassium hydroxide in aqueous methanol afforded novel N-alkyl/aryl thiatriazolophanes.

【 授权许可】

Unknown