Reaction of acyclic enaminones with methoxymethylene meldrum's acid: synthetic and structural implications

Journal of the Brazilian Chemical Society

Cunha, Silvio¹  Lariucci, Carlito¹  Universidade Federal de Goiás¹  Silva, Viviane C. da¹  Napolitano, Hamilton B.¹  Universidade Federal de Goiás, Goiânia, Brazil¹  Vencato, Ivo¹ 

关键词: enaminones;    Meldrum's acid;    aza-annulation;    2-pyridone;   

DOI  :  10.1590/S0103-50532003000100017

学科分类：化学（综合）

来源: SciELO

【 摘 要 】

The reaction of acyclic enaminones with methoxymethylene Meldrum's acid afforded N-adduct and/or C-adduct of enaminones in moderate to good yields. The regiochemistry of this reaction depends on the N-amino substituent of the enaminone. The C-adduct is a precursor to 2-pyridones. X-ray analysis of two N-adducts were investigated and the Z-s-Z configuration assigned.

【 授权许可】

Unknown