Are mice, rats, and rabbits good models for physiological, pharmacological and toxicological studies in humans?

Periodicum biologorum

BRZICA, HRVOJE¹  SABOLIĆ, IVAN¹  BRELJAK, DAVORKA¹  LJUBOJEVIĆ, MARIJA¹ 

[1] Unit of Molecular Toxicology Institute for Medical Research and Occupational Health, Ksaverska cesta 2, 10001 Zagreb, Croatia

关键词: experimental animals;    gender differences;    mammalian kidney;    nephrotoxicity;    organic anions;    organic cations;    proximal tubule;   

DOI  :  

学科分类：生物科学（综合）

来源: Periodicum Biologorum

【 摘 要 】

In the mammalian kidneys, handling of various organic compounds is mediated by multispecific organic anion and cation transporters localized in the luminal and contraluminal cell membrane domains of specific nephron segments, largely in...

【 授权许可】

Unknown