Assessment of hypolipidemic action of Talinum triangulare (water leaf) and Abelmoschus esculentus (okra)

Revista Cubana de Plantas Medicinales

Castillo Alfonso, Orestes¹  Santiesteban Muñoz, Dayli¹  González Madariaga, Yisel¹  Mena Linares, Yilka¹  Blanco Machado, Freisman¹ 

[1] Universidad de Ciencias Médicas de Villa Clara, Villa Clara, Cuba

关键词: talinum triangulare;    Abelmoschus esculentus;    sucrose-rich diet;    nonionic detergent;    experimental animals;   

DOI  :  

学科分类：药理学

来源: Editorial Ciencias Medicas

【 摘 要 】

Introduction: assessment of plants with low plasmatic lipids effect is a power instrument to dislipidemias control.Objectives: to establish the pharmacological effectiveness as hipolipidemic agents of Talinum triangulare (Jacq.) Willd (Portulacaceae) andAbelmoschus esculentus Moench (Malvaceae) in two biomodel assays.Methods: in the present study we have researched the hypolipemic effect of Talinum triangulare (false spinach) and A. esculentus (okra) in experimental animals subjected to two models of hyperlipidemia induction; an intake of 63 % sucrose solution for 16 weeks and an intake of Poloxamer 338 nonionic detergent via intraperitoneal for 48 hours at a dose of 0,6 g/kg.Results: the hydroalcoholic extract of A. esculentus, at a dose of 400 mg/kg showed triacilglicéridos reducing effect greater than nicotinic acid in the model of hyperlipidemia induction by a sucrose-rich diet. In the model of hyperlipidemia by induction with nonionic detergent, the hydroalcoholic extract of Talinum triangulare at a dose of 400 mg/kg, showed a powerful cholesterol and triacilglicéridos lowering effect, greater than nicotinic acid and atorvastatin.Conclusions: the hydroalcoholic extract of A. esculentus and T. triangulare showed hypotriglyceridemic effect for different action mechanisms, higher than the nicotinic acid, in each case. The extract hidroalcohólico of Talinum triangulare showed a potent hipocholesterolemic effect even more than the nicotinic acid and the atorvastatin.

【 授权许可】

CC BY-NC