1-Methylimidazolium trifluoroacetate [Hmim]Tfa: Mild and efficient Brønsted acidic ionic liquid for Hantzsch reaction under microwave irradiation

Journal of Chemical Sciences

Devji S Patel¹  Jemin R Avalani¹  Dipak K Raval1¹ 

[1] Department of Chemistry, Sardar Patel University, Vallabh Vidyanagar 388 120, India$$

关键词: 1;    4-Dihydropyridine;    Hantzsch synthesis;    [Hmim]Tfa;    homogeneous catalyst;    microwave;    multicomponent reaction.;   

DOI  :  

来源: Indian Academy of Sciences

【 摘 要 】

One pot synthesis of 1,4-dihydropyridine derivatives was achieved via condensation of various 𝛽-ketoesters with aromatic/aliphatic aldehydes and ammonium acetate. The reaction was catalysed by a stable and reusable Brønsted acidic ionic liquid (IL), 1-methyl-imidazolium trifluoroacetate ([Hmim]Tfa), under microwave (MW) irradiation. The synergistic combination ofMWwith IL can potentially go a long way tomeet the increasing demand for chemical processes. This homogeneous catalytic procedure is simple and efficient. The catalyst can be reused at least four times with almost complete retention in its activity.

【 授权许可】

Unknown