Mueller matrix polarimetry for the characterization of complex random medium like biological tissues

Pramana

M F G Wood²  Jalpa Soni¹  I A Vitkin²  Nirmalya Ghosh1¹  M A Wallenberg² 

[1] Department of Physical Sciences, Indian Institute of Science Education and Research, Kolkata 741 252, India$$;Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada$$

关键词: Scattering;    polarization;    Mueller matrix;    wave propagation in random media;    biomedical applications.;   

DOI  :  

学科分类：物理（综合）

来源: Indian Academy of Sciences

【 摘 要 】

The polarization parameters of light scattered from biological tissues contain wealth of morphological and functional information of potential biomedical importance. But, in optically thick turbid media such as tissues, numerous complexities due to multiple scattering and simultaneous occurrences of many polarization events present formidable challenges, in terms of both accurate measurement and unique interpretation of the individual polarimetry characteristics. We have developed and validated an expanded Mueller matrix decomposition approach to overcome this problem. The approach was validated theoretically with a polarization-sensitive Monte Carlo light propagation model and experimentally by recording Mueller matrices from tissue-like complex random medium. In this paper, we discuss our comprehensive turbid polarimetry platform consisting of the experimental polarimetry system, forward Monte Carlo modelling and inverse polar decomposition analysis. Initial biomedical applications of this novel general method for polarimetry analysis in random media are also presented.

【 授权许可】

Unknown