Functional magnetic resonance imaging of the primary motor cortex in humans: response to increased functional demands

Journal of biosciences

V Jain³  S S Kumaran¹  P C Jain²  R P Tripathi¹  S Khushu1¹  A Gupta¹ 

[1] NMR Research Centre, Institute of Nuclear Medicine and Allied Sciences, Lucknow Road, Delhi 110 054, India$$;Department of Physics and Astrophysics, University of Delhi, Delhi 110 007, India$$;BR Ambedkar Centre for Biomedical Research, University of Delhi, Delhi 110 007, India$$

关键词: Echo-planar imaging;    finger tapping frequency;    functional demand;    functional magnetic resonance imaging;    primary motor cortex;   

DOI  :  

来源: Indian Academy of Sciences

【 摘 要 】

Functional magnetic resonance imaging (fMRI) studies have been performed on 20 right handed volunteers at 1.5 Tesla using echo planar imaging (EPI) protocol. Index finger tapping invoked localized activation in the primary motor area. Consistent and highly reproducible activation in the primary motor area was observed in six different sessions of a volunteer over a period of one month. Increased tapping rate resulted in increase in the blood oxygenation level dependent (BOLD) signal intensity as well as the volume/area of activation (pixels) in the contralateral primary motor area up to tapping rate of 120 taps/min (2 Hz), beyond which it saturates. Activation in supplementary motor area was also observed. The obtained results are correlated to increased functional demands.

【 授权许可】

Unknown