Activation of left intraparietal sulcus using a fMRI conceptual praxis paradigm

Arquivos de Neuro-Psiquiatria

Jorge Moll¹  Ricardo De Oliveira-souza¹  Fabiana De Souza-lima¹  Pedro Angelo Andreiuolo¹ 

[1] ,Universidade Federal do Rio de Janeiro

关键词: conceptual apraxia;    intraparietal sulcus;    cerebral asymmetry;    functional magnetic resonance imaging;    apraxia conceitual;    sulco intraparietal;    assimetria cerebral;    ressonância magnética funcional;   

DOI  :  10.1590/S0004-282X1998000500017

来源: SciELO

【 摘 要 】

The present paper reports the results of a fMRI subtraction study of the pattern of cortical activation induced by an ideational praxis paradigm in six normal right-handed subjects. The control task consisted of a sequence of complex meaningless hand movements. A complete study was done for each hand in each subject. The left intraparietal sulcus was the only structure activated in all subjects regardless of the hand used in the task. These findings, albeit preliminary, suggest that the organization of actions involving the mediation of tools and utensils are strongly lateralized to the left hemisphere and that damage to the dominant intraparietal sulcus may be critical for the development of the clinical syndrome of conceptual apraxia.

【 授权许可】

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