The unmet need in rheumatology: reports from the Targeted Therapies meeting 2016

Clinical and Experimental Rheumatology

  Authors: Kevin L. Winthrop¹  Jonathan Kay¹  Philip J. Mease¹  Xavier Mariette¹  Maya H. Buch¹  Joan M. Bathon¹  Josef S. Smolen¹  Vibeke Strand¹  Ferry C. Breedveld¹  Mary K. Crow¹  Michael Weinblatt¹  Daniel E. Furst¹  Joachim R. Kalden¹  Désiréé M. van der Heijde¹  Gerd R. Burmester¹  Maxime Dougados¹ 

关键词: Rheumatoid arthritis;    Psoriatic arthritis;    Ankylosing spondylitis;    Spondyloarthritis;    Systemic lupus erythematosus;    Systemic sclerosis;   

DOI  :  

学科分类：医学（综合）

来源: Pacini Editore SpA

【 摘 要 】

Psoriatic arthritis (PsA) is a clinically heterogeneous condition of skin, joint, enthesis and bone that provides considerable unmet therapeutic need. Recent treatment advances have offered new opportunities to improve quality of life and long term well being for afflicted patients. It is timely therefore, to consider the underlying heterogeneity inherent in the disease from a pathologic aspect so as to best optimise the choice and order of therapeutic application over time. Herein I will discuss the various contributions made by immune pathways to discrete tissue compartments that in turn might allow a more targeted approach to the management of PsA in which different tissues express variable severity of involvement.

【 授权许可】

Unknown