Glucocorticoid-induced osteoporosis

Clinical and Experimental Rheumatology

Irene E.M. Bultink¹  Willem F. Lems¹  Debby den Uyl¹ 

关键词: Glucocorticoids;    osteoporosis;    bone;    Osteoporosis;    glucocorticoids;   

DOI  :  

学科分类：医学（综合）

来源: Pacini Editore SpA

【 摘 要 】

Glucocorticoid-induced osteoporosis is one of the most important side-effects of glucocorticoid use, leading to an increased fracture risk. In this review, recent advances in the understanding of the mechanisms of glucocorticoid-induced osteoporosis are summarised. Methods to identify persons at risk for fractures are discussed, as well as the new ACR recommendations for the prevention and treatment of glucocorticoid-induced osteoporosis (2010). Different treatment options are summarised considering the pathogenesis of glucocorticoid-induced osteoporosis. Improved insights into pathogenesis might result in development of new treatment possibilities.

【 授权许可】

Unknown