HIV/AIDS: epidemic update, new treatment strategies and impact on autoimmunity

Clinical and Experimental Rheumatology

M. Clerici¹  S. Piconi¹  P. Sarzi-Puttini¹  M. Galli¹  F. Atzeni¹  F. Croce¹ 

关键词: HIV;    autoimmunity;    lymphopenia;    antiretroviral therapy.;   

DOI  :  

学科分类：医学（综合）

来源: Pacini Editore SpA

【 摘 要 】

ABSTRACT: Human Immunodeficiency Virus (HIV) infection represents one of the most serious challenges to global public health, since more than 30 million people are living with HIV/AIDS worldwide. Highly active antiretroviral treatment (HAART) introduction has dramatically changed the mortality and morbidity of HIV-affected subjects in industrialized countries but has implied an evolution of many HIV-related aspects, both in the utilisation of new antiretroviral drugs options and in the newly-observed spectrum of HIV-associated diseases, including the rheumatic pathology. Current epidemiological, therapeutic, autoimmune and rheumatic aspects of HIV-1 infection are here discussed.

【 授权许可】

Unknown