Normalization of nomenclature for peptide motifs as ligands of modular protein domains

FEBS Letters

Aasland, Rein⁴  Gimona, Mario⁸  Bedford, Mark T.¹  Abrams, Charles²  Jarchau, Thomas⁶  Ampe, Christophe^1,10  Lehto, Veli-Pekka⁹  Mayer, Bruce J.⁷  Nagai, Makoto^1,15  Cesareni, Gianni^1,14  Ball, Linda J.⁵  Linding, Rune^1,11  Sudol, Marius^1,15  Winder, Steve J.^1,12  Lemmon, Mark A.³  Hurley, James H.^1,13  Walter, Ulrich⁶ 

[1] Department of Carcinogenesis, University of Texas, Smithville, TX 78957, USA;Division of Hematology and Oncology, University of Pennsylvania, Philadelphia, PA 19014, USA;Department of Biochemistry and Biophysics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA;Department of Molecular Biology, University of Bergen, 5020 Bergen, Norway;Department of NMR and Structural Biology, F.M.P. – Research Institute of Molecular Pharmacology, D-13125 Berlin, Germany;Institut für Klinische Biochemie und Pathobiochemie, D-97078 Würzburg, Germany;Department of Genetics and Developmental Biology, University of Connecticut, Farmington, CT 06030, USA;Department of Cell Biology, Austrian Academy of Sciences, 5020 Salzburg, Austria;Department of Pathology, University of Oulu, 90410 Oulu, Finland;Department of Biochemistry, Ghent University, B-9000 Gent, Belgium;Biocomputing Unit, EMBL, D-69117 Heidelberg, Germany;Division of Biochemistry and Molecular Biology, University of Glasgow, Glasgow G12 8QQ, UK;Laboratory of Molecular Biology, National Institutes of Health, NIDDK, Bethesda, MD 20892, USA;Department of Biology, Unviversity of Rome, Tor Vergata, 00133 Rome, Italy;Department of Medicine, Mt. Sinai Medical Center, New York, NY 10029, USA

关键词: Protein–protein interaction;    Peptide motif;    Protein domain;    specificity and recognition;    Proteomics;    Glossary;    Nomenclature;    ASCII format;   

DOI  :  10.1016/S0014-5793(01)03295-1

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

We propose a normalization of symbols and terms used to describe, accurately and succinctly, the detailed interactions between amino acid residues of pairs of interacting proteins at protein:protein (or protein:peptide) interfaces. Our aim is to unify several diverse descriptions currently in use in order to facilitate communication in the rapidly progressing field of signaling by protein domains. In order for the nomenclature to be convenient and widely used, we also suggest a parallel set of symbols restricted to the ASCII format allowing accurate parsing of the nomenclature to a computer-readable form. This proposal will be reviewed in the future and will therefore be open for the inclusion of new rules, modifications and changes.

【 授权许可】

Unknown