Crystal structure of a cyclic form of bovine pancreatic trypsin inhibitor

FEBS Letters

Botos, Istvan²  Wu, Zhibin¹  Lu, Wuyuan¹  Wlodawer, Alexander² 

[1] Institute of Human Virology, University of Maryland, Baltimore, MD 21201, USA;Protein Structure Section, Macromolecular Crystallography Laboratory, National Cancer Institute at Frederick, Frederick, MD 21702, USA

关键词: Bovine pancreatic trypsin inhibitor;    Cyclic protein;    Atomic resolution;   

DOI  :  10.1016/S0014-5793(01)03113-1

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The crystal structure of a cyclic form of a mutant of bovine pancreatic trypsin inhibitor has been solved at 1.0 Å resolution. The protein was synthesized by native chemical ligation and its structure is almost indistinguishable from the previously described recombinant form of the same mutant; however, the new loop containing the former termini became much better ordered.

【 授权许可】

Unknown