Ferredoxins of the third kind

FEBS Letters

Meyer, Jacques¹ 

[1] Laboratoire de Bioénergétique Cellulaire et Pathologique, Département de Biologie Moléculaire et Structurale, CEA-Grenoble, 38054 Grenoble, France

关键词: Iron–sulfur;    Electron transfer;    Complex I;    Hydrogenase;    Thioredoxin;    Evolution;   

DOI  :  10.1016/S0014-5793(01)03049-6

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Most low-potential ferredoxins (Fds) are of the well-known [2Fe–2S] plant or [4Fe–4S] bacterial type. Yet, an additional class of [2Fe–2S] Fds has been recognized on the basis of sequence and spectroscopic idiosyncrasies. A recent crystal structure has confirmed the uniqueness of this third kind of Fd, and shown that these proteins display an unexpected structural similarity to thioredoxin. The properties of these thioredoxin-like [2Fe–2S] Fds are summarized, and hypotheses concerning their function are discussed.

【 授权许可】

Unknown