Existence of Na+‐translocating NADH‐quinone reductase in Haemophilus influenzae

FEBS Letters

Nakayama, Yuji¹  Hayashi, Maki¹  Unemoto, Tsutomu¹ 

[1] Laboratory of Membrane Biochemistry, Faculty of Pharmaceutical Sciences, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba 263, Japan

关键词: Na+ pump;    Na+-translocating NADH-quinone reductase;    Haemophilus influenzae;    nqr Operon;    Complex I;    Vibrio alginolyticus;   

DOI  :  10.1016/0014-5793(96)00114-7

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

We previously cloned and sequenced nqr operon encoding the Na⁺-translocating NADH-quinone reductase (NQR) from the marine bacterium Vibrio alginolyticus. A gene cluster very similar to nqr operon was found to exist in the genome of Haemophilus influenzae Rd. We examined the membrane fraction from H. influenzae, and the respiratory chain of H. influenzae was found to contain a Na⁺-dependent NQR that is essentially identical to those found in the marine V. alginoltyticus. These results indicate that quite similar to the salt-loving marine bacteria, the blood-loving H. influenzae has a redox-driven Na⁺ pump and utilizes Na⁺ circulation for energy coupling.

【 授权许可】

Unknown