2‐Chloro‐1,4‐dimethoxybenzene as a mediator of lignin peroxidase catalyzed oxidations

FEBS Letters

Teunissen, Pauline J.M¹  Field, Jim A¹ 

[1] Division of Industrial Microbiology, Department of Food Technology and Nutritional Sciences, Wageningen Agricultural University, P.O. Box 8129, 6700 EV Wageningen, The Netherlands

关键词: Lignin peroxidase;    2-Chloro-1;    4-dimethoxybenzene;    Mediator;    Poly R-478;    4-Methoxy mandelic acid;    Bjerkandera sp. BOS55;    LiP;    lignin peroxidase;    2Cl-14DMB;    2-chloro-1;    4-dimethoxybenzene;    VA;    veratryl alcohol;    2Cl-14BQ;    2-chloro-1;    4-benzoquinone;    4-MMA;    4-methoxymandelic acid;    14DMB;    1;    4-dimethoxybenzene;    AAld;    anisaldehyde;   

DOI  :  10.1016/S0014-5793(98)01386-6

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Poly R-478, 4-methoxymandelic acid and oxalic acid were oxidized by lignin peroxidase (LiP) in the presence of the fungal metabolite 2-chloro-1,4-dimethoxybenzene (2Cl-14DMB), whereas no oxidation occurred in the absence of 2Cl-14DMB. These substrates clearly inhibited the consumption of 2Cl-14DMB and the formation of 2-chloro-1,4-benzoquinone from 2Cl-14DMB by LiP. The results suggest that 2Cl-14DMB can replace the function of veratryl alcohol as a redox mediator in lignin peroxidase catalyzed oxidations.

【 授权许可】

Unknown