Crystal structure of rabbit muscle creatine kinase

FEBS Letters

Mohana Rao, J.K¹  Wlodawer, Alexander¹  Bujacz, Grzegorz¹ 

[1] Macromolecular Structure Laboratory, NCI-Frederick Cancer Research and Development Center, ABL-Basic Research Program, Frederick, MD 21702, USA

关键词: Creatine kinase;    Rabbit muscle;    Enzyme;    Crystal structure;   

DOI  :  10.1016/S0014-5793(98)01355-6

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The crystal structure of rabbit muscle creatine kinase, solved at 2.35 Å resolution by X-ray diffraction methods, clearly identified the active site with bound sulfates surrounded by a constellation of arginine residues. The putative binding site of creatine, which is occupied by a sulfate group in this analysis, has been tentatively identified. The dimeric interface of the enzyme is held together by a small number of hydrogen bonds.

【 授权许可】

Unknown