Anti-fatigue Effects of Polysaccharide from Angelica Sinensis

International Conference on Manufacturing Technology, Materials and Chemical Engineering

机械制造;材料科学;化学工业

Liu, Qiang^1 ; Li, Yajun^1

Department of Physical Education and Research, Central South University, Changsha, Hunan

410083, China^1

关键词: Angelica sinensis;    Biochemical parameters;    Creatine kinase;    Distilled water;    Lactic acid production;    Muscle glycogens;    Normal controls;    Urea nitrogen;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/392/5/052011/pdf
DOI  :  10.1088/1757-899X/392/5/052011

学科分类：材料科学（综合）

来源: IOP

【 摘 要 】

The present study was designed to investigate the anti-fatigue effects of polysaccharides from A. sinensis (APS). The mice were divided into 4 groups: normal control, low, middle, and high-dose APS treated group. Normal control group was treated with distilled water, while APS treated groups received different doses of APS by oral gavage once daily for 28 day. The anti-fatigue effects were evaluated using the forced swimming test, along with the determination of exhaustive swimming times and fatigue related biochemical parameters such as blood lactic acid, serum urea nitrogen, liver glycogen, muscle glycogen, and serum creatine kinase. The data showed that APS could prolong the exhaustive swimming times in mice, reduce blood lactic acid production or promote blood lactic acid elimination, as well as decrease the serum urea nitrogen contents, and increase contents of liver and muscle glycogen. Therefore, APS has anti-fatigue effects.