期刊论文详细信息
FEBS Letters | |
Somatic and germline clone analysis in mutants of the S‐adenosylmethionine synthetase encoding gene in Drosophila melanogaster | |
Rasmuson-Lestander, Åsa1  Larsson, Jan1  | |
[1] Department of Genetics, Umeå University, S-901 87 Umeå, Sweden | |
关键词: S-Adenosylmethionine synthetase; Polyamine synthesis; Protein synthesis; Drosophila melanogaster; | |
DOI : 10.1016/S0014-5793(98)00408-6 | |
学科分类:生物化学/生物物理 | |
来源: John Wiley & Sons Ltd. | |
【 摘 要 】
We have analysed the phenotypic consequences of homozygous mutant clones in the S-adenosylmethionine synthetase encoding gene in Drosophila melanogaster. The results suggest that SamS function is required for cell proliferation/growth in embryonic/early larval cells and during development of imaginal disc cells. Homozygous SamS germline clones can, however, develop and give rise to viable heterozygous offspring. This offspring expresses a Minute-like phenotype. We suggest that this phenotype is caused by an obstruction of the polyamine biosynthesis.
【 授权许可】
Unknown
【 预 览 】
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