ABI1 of Arabidopsis is a protein serine/threonine phosphatase highly regulated by the proton and magnesium ion concentration

FEBS Letters

Leube, M.P²  Amrhein, N²  Grill, E¹ 

[1] Lehrstuhl für Botanik, Technische Universität München, Arcisstrasse 16, D-80333 Munich, Germany;Institut für Pflanzenwissenschaften, Eidgenössische Technische Hochschule Zürich, Universitätsstrasse 2, CH-8092 Zürich, Switzerland

关键词: Protein phosphatase 2C;    Signal transduction;    Stoma;    Dominant negative phenotype;    Arabidopsis thaliana;   

DOI  :  10.1016/S0014-5793(98)00149-5

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The plant hormone abscisic acid (ABA) mediates various responses such as stomatal closure, maintenance of seed dormancy, and inhibition of plant growth. All three responses are regulated by the ABI1 gene product. The ABI1 protein (ABI1p) has been characterized as a protein serine/threonine phosphatase of type 2C that is highly affected in its activity by changes in the proton and magnesium ion concentrations. In the ABA-insensitive mutant abi1 of Arabidopsis thaliana a single amino acid exchange in the primary structure results in both a dominant insensitive phenotype and a strongly reduced protein phosphatase activity in vitro by possibly impairing metal ion coordination.

【 授权许可】

Unknown