ABI2, a second protein phosphatase 2C involved in abscisic acid signal transduction in Arabidopsis

FEBS Letters

Benning, Gregor¹  Rodriguez, Pedro L¹  Grill, Erwin¹ 

[1] TU-München, Lehrstuhl für Botanik, Arcisstrasse 16, D-80333 Munich, Germany

关键词: Abscisic acid;    Protein phosphatase 2C;    Signal transduction;    ABI2;    ABI1;   

DOI  :  10.1016/S0014-5793(97)01558-5

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The abi2-1 (abscisic acid insensitive) mutant of Arabidopsis thaliana shows abscisic acid (ABA) insensitivity with respect to seed germination and vegetative ABA responses. We identified the ABI2 gene by a combination of positional mapping and homology to ABI1. The ABI2 protein shows 80% amino acid sequence identity to ABI1, a protein phosphatase 2C (PP2C) involved in ABA signaling. The mutation that confers the abi2-1 phenotype is equivalent to the mutation previously identified in abi1-1 and the resulting Gly¹⁶⁸Asp abi2 protein shows a reduced PP2C activity. Thus, a pair of highly homologous PP2Cs regulate ABA signaling.

【 授权许可】

Unknown