The hsc70 gene which is slightly induced by heat is the main virus inducible member of the hsp70 gene family

FEBS Letters

Angelidis, Charalambos¹  Sainis, Ioannis¹  Pagoulatos, Gerassimos¹  Lazaridis, Ioannis¹ 

[1] Laboratory of General Biology, Medical School, University of Ioannina, GR 45332 Ioannina, Greece

关键词: hsc70;    hsp70;    SV40;    Cell cycle;   

DOI  :  10.1016/0014-5793(94)01210-5

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

We have found that SV40 infection of CV1 cells induces the synthesis of a 72 kDa protein that upon molecular cloning was shown to be the product of the hsc70 gene. The above gene product was found to be mainly virus inducible, in contrast to the hsp70 gene product which was mainly heat inducible. The two genes were found to be cell cycle regulated in a distinctively different manner.

【 授权许可】

Unknown