Distinct expression of two Drosophila homologs of fibroblast growth factor receptors in imaginai discs

FEBS Letters

Saigo, Kaoru¹  Emori, Yasufumi¹ 

[1] Department of Biophysics and Biochemistry, Faculty of Science, University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo 113, Japan

关键词: Fibroblast growth factor;    Fibroblast growth factor receptor;    Drosophila melanogaster;    Imaginal disc;    In situ hybridization;   

DOI  :  10.1016/0014-5793(93)80494-F

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The expression of two Drosophila homologs of FGF receptors (DRF1 and DRF2) in imaginal discs was studied. DFR1 mRNA was observed in several imaginal discs, whereas DFR2 mRNA was not detected. DFR1 expression in the wing and leg discs took place in probable myoblasts in a pattern similar to that of twist, a mesodermal gene. The mRNA was also detected in the morphogenetic furrow and its posterior region of the eye disc and around the proliferation center of the brain. These results suggest that DFR1 is involved in the development of mesodermal and neuronal cells constituting the adult body.

【 授权许可】

Unknown