A new perspective on muscle contraction

FEBS Letters

Lindberg, Uno²  Schutt, Clarence E.¹ 

[1] The Henry H. Hoyt Laboratory, Washington Road, Princeton University, Princeton, NJ 08544, USA;Zoological Cell Biology, WGI, Arrhenius Laboratories for Natural Sciences, Stockholm University, S-10691 Stockholm, Sweden

关键词: Muscle contraction;    Fenn effect;    Actin power-stroke;    Myosin power-stroke;    Force generation;    Tropomyosin;   

DOI  :  10.1016/0014-5793(93)81413-T

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Recent experimental findings suggest that the myosin cross-bridge theory may no longer be adequate to account for certain basic facts concerning muscle contraction. A newly-proposed mechanism based on length changes in actin filaments might be the basis for a simpler explanation for how the free energy of ATP hydrolysis can be transduced into work by muscle fibers.

【 授权许可】

Unknown