Multiple genes for G protein‐coupled receptors and their expression in lingual epithelia

FEBS Letters

Arai, Soichi²  Tanemura, Kentaro³  Abe, Keiko²  Kusakabe, Yuko²  Emori, Yasufumi¹ 

[1] Department of Biophysics and Biochemistry, Faculty of Science, University of Tokyo, Bunkyo, Tokyo 113, Japan;Department of Agricultural Chemistry, University of Tokyo, Bunkyo, Tokyo 113, Japan;Department of Veterinary Anatomy, Faculty of Agriculture University of Tokyo, Bunkyo, Tokyo 113, Japan

关键词: Taste receptor;    G protein-coupled receptor;    Lingual epithelium;    Polymerase chain reaction;   

DOI  :  10.1016/0014-5793(93)81302-G

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Using the polymerase chain reaction (PCR), we identified a gene family including more than 60 members which encoded similar G protein-coupled seven-transmembrane receptors. Sequence analyses of six representatives out of the 60 PCR clones showed that they had significant structural similarity to olfactory and optic receptors. Their expression is restricted in the surface of lingual epithelia.

【 授权许可】

Unknown