Ca2+‐mediated interaction between negatively charged and neutral liposomes

FEBS Letters

Sokoloff, Alexander V.²  Budker, Vladimir G.²  Kiseleva, Helena V.¹  Serebryakova, Marina V.² 

[1] Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russian Federation;Institute of Bioorganic Chemistry, Siberian Division of the Russian Academy of Sciences, Novosibirsk, Russian Federation

关键词: Liposome;    Divalent cation;    Intermembrane interaction;    LUV;    large unilamellar vesicle;    SUV;    small unilamellar vesicle;    Me2+;    divalent metal ions;    DPPC;    1;    2-dipalmitoyl-sn-glycero-3-phosphocholine;    DCP;    dicetyl phosphate;    PC;    egg yolk phosphatidylcholine;    PE;    egg yolk phosphatidylethanolamine;    Rd-DPPE;    N-(lissamine rhodamine B sulfonyl)dipalmitoyl-l-α-phosphatidylethanolamine;    Br-R-N-O;    4-bromomethyl 2;    2;    3;    5;    5-pentamethylimidazolidin-1-oxyl;    NBD;    7-chloro-4-nitrobenz-2-oxa-1;    3-diazole;    CF;    carboxyfluorescein;    ESR;    electron spin resonance;    EM;    electron microscopy;    RET;    resonance energy transfer.;   

DOI  :  10.1016/0014-5793(92)81437-Q

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

In the present work it is shown that large unilamellar lecithin/cholesterol liposomes are able to sequester small negatively charged liposomes in the presence of divalent cations. Evidence is presented suggesting that the sequestration occurs via the formation of membrane invaginations transformed further into intraliposomal vesicles.

【 授权许可】

Unknown