The gene structure of tetranectin, a plasminogen binding protein

FEBS Letters

Petersen, Torben E.¹  Berglund, Lars¹ 

[1] Department of Molecular Biology, University of Aarhus, C.F. Mollers Allè 130, DK-8000, Aarhus C, Denmark

关键词: Tetranectin;    Cloning;    Expression;    Oligonucleotide probe;    Plasminogen binding;    kbp;    kilo base pairs;    nt;    nucleotides;   

DOI  :  10.1016/0014-5793(92)80729-Z

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The gene for human tetranectin was isolated from a genomic library with a mixture of degenerate oligonucleotide probes. The gene is about 12 kbp and contains two intervening sequences. The gene encodes a protein of 202 amino acid residues, with a signal peptide of 21 amino acid residues, followed by the tetranectin sequence of 181 amino acid residues. Northern blot analysis revealed that tetranectin mRNA was present in all eight tissues tested with the highest concentration in lung. Southern blot analysis showed hybridization to two genes. Further investigations are needed to determine whether the genes are allelic or non-allelic.

【 授权许可】

Unknown