Purification and characterization of a Kunitz‐type trypsin inhibitor from Leaf‐nosed viper venom

FEBS Letters

Zaidi, Zafar H.¹  Siddiqi, Abdur Rehman¹  Jörnvall, Hans¹ 

[1] Department of Chemistry I, Karolinska Institutet, S-104 01 Stockholm, Sweden

关键词: Trypsin inhibitor;    Amino acid sequence;    C-terminal extension;    Contact site;    Homology;   

DOI  :  10.1016/0014-5793(91)81361-B

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

A Kunitz-type trypsin inhibitor was purified from Leaf-nosed viper venom and the primary structure determined by peptide analysis. In relation to other trypsin inhibitors, the protein has an extended C-terminal segment and a distinct pattern of residue alterations at the functionally important contact sites with proteases.

【 授权许可】

Unknown