Pentasialogangliosides of human brain

FEBS Letters

Miller-Podraza, Halina¹  Svennerholm, Lars¹  Månsson, Jan-Eric¹ 

[1] Department of Psychiatry and Neurochemistry, University of Göteborg, St. Jörgen Hospital, S-422 03 Hisings Backa, Sweden

关键词: Complex ganglioside;    Pentasialoganglioside;    Complex glycosphingolipid;    Human brain;    Human cerebellum;    NeuAc;    N-acetylneuraminic acid;    Ga1;    galactose;    G1c;    glucose;    HexNAc;    N-acetylhexosamine;    Ga1NAc;    N-acetylgalactosamine. The ganglioside nomenclature is according to Svennerholm (Eur. J. Biochem. (1977) 79;    11–21). GP1;    pentasialoganglioside;    GP1b;    IV3(NeuAc)3II3(NeuAc)2GgOse4Cer;    BP1c;    IV3(NeuAc)2II3-(NeuA)3GgOse4Cer;   

DOI  :  10.1016/0014-5793(91)81036-8

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

A pentasialoganglioside fraction of the ganglio series of glycosphingolipids has been isolated from human cerebellar cortex with a yield of 8.8 nmol NeuAc per g fresh tissue. The structural analysis showed that the material was a mixture of GP1b and GP1c gangliosides.

【 授权许可】

Unknown