Novel structurally distinct family of leucocyte surface glycoproteins including CD9, CD37, CD53 and CD63

FEBS Letters

Hořejši, Václav¹  Vlček, Čestmir¹ 

[1] Institute of Molecular Genetics, Czechoslovak Academy of Sciences, 142 20 Prague, Czechoslovakia

关键词: Leucocyte surface glycoprotein;    CD9;    CD37;    CD53;    CD63;    Integral membrane protein;   

DOI  :  10.1016/0014-5793(91)80988-F

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Several of the recently described leucocyte surface (glyco)-proteins with significant amino acid sequence similarity (human CD9, CD37, CD53, CD63, TAPA-1, CO-029 and R2 and several homologues of other species) are distinguished by the polypeptide chain apparently four times crossing the membrane. Although the biological role of none of these molecules is known, their structure, associations with other membrane components and the effects of specific monoclonal antibodies suggest that they may constitute a family of ion channels or other transport molecules.

【 授权许可】

Unknown