Ca2+‐storage organelles

FEBS Letters

Krause, Karl-Heinz¹ 

[1] Division of Infectious Diseases, Department of Internal Medicine, University Hospital, Geneva, Switzerland

关键词: Ca2+ pump;    Ca2+ release channel;    Ca2+ storage protein;    Sarcoplasmic reticulum;    Calsiosome;    Endoplasmic reticulum;   

DOI  :  10.1016/0014-5793(91)80806-E

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Intracellular Ca²⁺-storage organelles are found in virtually all eukaryotic cells. They play an important role in the regulation of the cytosolic free Ca²⁺ concentration and, thereby, in the regulation of cellular activity. Ca²⁺-storage organelles consist, in the simplest model of a Ca²⁺ pump, of a Ca²⁺-storage protein and a Ca²⁺-release channel. The primary structure of these functionally important proteins of Ca²⁺-storage organelles is similar in different cell types and conserved through evolution. In contrast, their spatial arrangement and, thus, the architecture of Ca²⁺-storage organelles may vary dramatically from one cell type to another.

【 授权许可】

Unknown