Effects of anions on the Ca2+, H+ and electrical gradients formed by the sarcoplasmic reticulum ATPase in reconstituted proteoliposomes

FEBS Letters

Yu, Xiang¹  Inesi, Giuseppe¹ 

[1] Department of Biological Chemistry, University of Maryland School of Medicine, Baltimore, MD 21201, USA

关键词: Anion;    Sarcoplasmic reticulum;    Ca2+ pump;   

DOI  :  10.1016/0014-5793(93)80948-T

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The chaotropic character of several ions determines their partition on membrane interfaces with aqueous media as predicted by the Hofmeister series. However, specific characteristics of each individual ion determine its ability to cross the membrane and to influence Ca²⁺, H⁺ and electrical gradients produced by the sarcoplasmic reticulum (SR) Ca²⁺ pump in reconstituted proteoliposomal vesicles. Specific effects of this kind may be relevant to a variety of biological systems, including the excitation-contraction coupling of muscle fibers in which SR plays a prominent role.

【 授权许可】

Unknown