Characterization of a protein that appears in the nervous system of the moth Manduca sexta coincident with neuronal death

FEBS Letters

Giometti, Carol S.¹  Fahrbach, Susan E.²  Roy, Edward J.²  Montemayor, Michelle E.² 

[1] Biological and Medical Research Division, Argonne National Laboratory, Argonne, IL 60439, USA;Neuroscience Program, University of Illinois at Urbana-Champaign, Champaign, IL 61820 USA

关键词: Neuronal death;    Gel electrophoresis;    2-D;    Cell death;    Metamorphosis;    Protein synthesis;    Abdominal ganglia;    Manduca sexta;   

DOI  :  10.1016/0014-5793(90)80546-U

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Two-dimensional gel electrophoresis was used to locate potential neuronal death-related proteins in the moth Manduca sexta. Protein patterns of ganglia of pharate adult moths (taken prior to adult ecdysis) compared with protein patterns of one-day-old adults revealed reproducible changes in protein patterns. An acidic protein of approximately 40000 Da was present in all samples from adult moths undergoing neuronal death and essentially absent from pharate adult samples.

【 授权许可】

Unknown