FEBS Letters | |
The hexose carrier from Chlorella | |
Sauer, Norbert1  Tanner, Widmar1  | |
[1] Lehrstuhl für Zellbiologie und Pflanzenphysiologie, Universität Regensburg, 8400 Regensburg, FRG | |
关键词: Cotransporter; H+/hexose; Differential screening; (Chlorella kessleri); | |
DOI : 10.1016/0014-5793(89)81489-9 | |
学科分类:生物化学/生物物理 | |
来源: John Wiley & Sons Ltd. | |
【 摘 要 】
The cDNA coding for the inducible H+/hexose cotransporter of Chlorella kessleri has been cloned and sequenced. It was isolated by differential screening of a cDNA library prepared from glucose-induced cells. The increase in expression of the gene correlates quantitatively with the increase in uptake activity due to induction; it is not expressed in a hexose transport mutant. An open reading frame allows for a membrane protein of 533 amino acids with a relative molecular mass of 57 kDa. This protein is highly homologous to the human and rat glucose transporters catalyzing facilitated diffusion and to the bacterial H+/pentose cotransporters. It is not related to the H+/lactose cotransporter of E.colli and to the mammalian Na+/glucose cotransporter.
【 授权许可】
Unknown
【 预 览 】
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