期刊论文详细信息
FEBS Letters | |
Activation of chloride channels in the plasmalemma of Nitella syncarpa by inositol 1,4,5‐trisphosphate | |
Zherelova, O.M.1  | |
[1] Institute of Biological Physics, Academy of Sciences of the USSR, Pushchino, Moscow Region 142292, USSR | |
关键词: Inositol 1; 4; 5-trisphosphate; Ca2+; Ionic channel; (Characeae; Nitella syncarpa); | |
DOI : 10.1016/0014-5793(89)80025-0 | |
学科分类:生物化学/生物物理 | |
来源: John Wiley & Sons Ltd. | |
【 摘 要 】
The introduction of 1.5 × 10−8 − 10−6 M inositol 1,4,5-trisphosphate (IP3) into the bathing solution of Nitella syncarpa cells induced: (i) an increase in amplitude of the inward Ca2+ current; (ii) the appearance of an inward Cl− current; (iii) a shift in the threshold for activation of the Cl− channels on hyperpolarization of the membrane to more positive values. These facts suggest that IP3 participates in the causing of changes in the intracellular free Ca2+ concentration and, hence, in the regulation of ionic channels in Nitella syncarpa plasmalemma.
【 授权许可】
Unknown
【 预 览 】
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