87Rb NMR studies of the perfused rat heart

FEBS Letters

Allis, Jonathan L.¹  Seymour, Anne-Marie L.¹  Snaith, Christine D.¹  Radda, George K.¹ 

[1] Department of Biochemistry, University of Oxford, South Parks Rd, Oxford OX1 3QU, England

关键词: NMR;    Rubidium kinetics;    Potassium flux;    (Isolated perfused rat heart);   

DOI  :  10.1016/0014-5793(89)80472-7

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

We have studied ⁸⁷Rb⁺ fluxes in the perfused rat heart using nuclear magnetic resonance spectroscopy (NMR). A simple model for the interpretation of the data is presented. A comparison of radioactively measured K⁺ fluxes and the K⁺ fluxes deduced from the ⁸⁷Rb⁺ measurements shows them to be very similar. This method provides a means of noninvasively measuring uni-directional K⁺ fluxes in the heart.

【 授权许可】

Unknown