Identification of the human hepatic microsomal glucose‐6‐phosphatase enzyme

FEBS Letters

Countaway, Janice L.³  Hume, Robert²  Waddell, Ian D.¹  Arion, William J.³  Burchell, Ann¹ 

[1] Department of Medicine, Ninewells Hospital and Medical School, Dundee DD1 9SY, Scotland;Department of Child Life and Health, University of Edinburgh, Edinburgh EH3 9EF, Scotland;Division of Nutritional Sciences and the Section of Biochemistry, Molecular and Cell Biology, Cornell University, Ithaca, NY 14853, USA

关键词: Glucose-6-phosphatase;    Glycogen storage disease;    Phosphohydrolase;    (Liver microsome);   

DOI  :  10.1016/0014-5793(88)81005-6

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The glucose-6-phosphatase enzyme protein of the human hepatic microsomal glucose-6-phosphatase system was identified as a 36.5 kDa polypeptide. The 36.5 kDa glucose-6-phosphatase enzyme protein was shown to be absent in the microsomes isolated from a patient previously diagnosed as having a type 1a glycogen storage disease.

【 授权许可】

Unknown