The identification of T2; the phosphate/pyrophosphate transport protein of the hepatic microsomal glucose‐6‐phosphatase system

FEBS Letters

Lindsay, J.Gordon¹  Waddell, Ian D.²  Burchell, Ann² 

[1] Department of Biochemistry, University of Glasgow, Glasgow G12 8QQ, Scotland;Department of Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, Scotland

关键词: Glucose-6-phosphatase;    Glycogen storage disease;    Phosphate transport;    (Liver microsome);   

DOI  :  10.1016/0014-5793(88)80822-6

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The phosphate/pyrophosphate translocase protein (T₂) of the hepatic microsomal glucose-6-phosphatase system was identified and then purified using antibodies raised against the rat mitochondrial phosphate/hydroxyl ion antiport protein. The T₂ protein was shown to be absent in the microsomes isolated from a patient previously diagnosed as having type 1c glycogen storage disease.

【 授权许可】

Unknown