Identification of lysine residue 199 of human serum albumin as a binding site for benzylpenicilloyl groups

FEBS Letters

Yvon, Mireille¹  Wal, Jean-Michel¹ 

[1] Laboratoire des Sciences de la Consommation, INRA — CRJ, 78350 Jouy-en-Josas, France

关键词: Albumin;    Penicillin;    Benzylpenicilloyl;    Lysine;   

DOI  :  10.1016/0014-5793(88)80924-4

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Cyanogen bromide and tryptic fragments of penicilloylated serum albumin from penicillin-treated patients were separated by HPLC. Determinations of benzylpenicilloyl (BPO) were performed on the different fractions. A BPO containing peptide was identified by its amino acid sequence and the bound BPO group was located on the lysine residue 199.

【 授权许可】

Unknown