Location of penicilloyl groups on CNBr fragments of the albumin from penicillin‐treated patients

FEBS Letters

Lafaye, Pierre¹  Lapresle, Claude¹ 

[1] Service d'Immunochimie des Protéines, Institut Pasteur, 75724 Paris Cédex 15, France

关键词: Albumin;    Penicillin;    Penicilloyl group;    (Human serum);   

DOI  :  10.1016/0014-5793(87)80904-3

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Two fixation sites for penicilloyl groups on human albumin were demonstrated. Using CNBr cleavage the first site was located between methionine 123 and methionine 297 and the second one between methionine 297 and the C-terminal residue. In both cases, penicilloyl groups were unmasked by pronase degradation or disulfide bond reduction.

【 授权许可】

Unknown