K+ channels activated by L‐alanine transport in isolated Necturus enterocytes

FEBS Letters

Sepúlveda, F.V.²  Sheppard, D.N.²  Giraldez, F.¹ 

[1] Departamento de Bioquimica y Biologia Molecular y Fisiologia, Facultad de Medicina, Universidad de Valladolid, 47005 Valladolid, Spain;AFRC Institute of Animal Physiology and Genetics Research, Babraham, Cambridge CB2 4AT, England

关键词: K+ channel;    Ca2+;    L-Alanine;    Patch-clamp;    (Necturus enterocyte);   

DOI  :  10.1016/0014-5793(88)80134-0

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Using the patch-clamp technique, we demonstrate here the opening of K⁺ channels evoked by the actively transported amino acid L-alanine in isolated Necturus enterocytes. These channels had a conductance of about 30 pS and their activation was dependent on transmembrane electrical potential and cytosolic Ca²⁺.

【 授权许可】

Unknown