DNA cleavage based on high voltage electric pulse

FEBS Letters

Tamiya, Eiichi¹  Karube, Isao¹  Nakajima, Yoshiko¹  Kamioka, Hiroyuki¹  Suzuki, Masayasu¹ 

[1] Research Laboratory of Resources Utilization, Tokyo Institute of Technology, 4259 Nagatsuta, Midori-ku, Yokohama, Japan

关键词: Electrochemistry;    Oxygen radical;    DNA cleavage;    ESR;    Electric pulse;    Radical scavenger;   

DOI  :  10.1016/0014-5793(88)80116-9

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

A high voltage electric pulse was applied to DNA cleavage. The DNA cleavage reaction was dependent on the voltage amplitude, pulse number and pulse width. Radical scavengers and ESR data indicated the possibility that active species such as OH radical were strongly related to DNA cleavage.

【 授权许可】

Unknown